Dosing Tables by Weight
| Ketamine at 3 micrograms/kg/minute | See Table |
| Ketamine at 4 micrograms/kg/minute | See Table |
| Hydromorphone at 0.01 mg/kg/hr | See Table |
Chronic Pain and Ketamine
Maximize your clinic's impact on canine chronic pain with the Mini-Infuser drug delivery pump, providing precise ketamine infusions that target NMDA receptors to reverse central sensitization. This advanced system offers a transformative, multimodal solution for treating maladaptive pain and improving long-term quality of life for veterinary patients.
| Dr. Lindsey Fry, DVM, cVMA, CCRP, CVPP | A Novel Approach with a Familiar Tool—Part 1 Review of Ketamine and Chronic Pain | Read Paper |
| Dr. Lindsey Fry, DVM, cVMA, CCRP, CVPP | A Novel Approach with a Familiar Tool—Part 2 Clinical Application and Case Studies | Read Paper |
| Dr. Lindsey Fry, DVM, cVMA, CCRP, CVPP | Ketamine and Maladaptive Pain | Watch Video |
Acute Pain and Hydromorphone
The RxActuator Mini-Infuser® provides a solution for outpatient canine pain management by delivering a consistent 48-hour subcutaneous infusion of hydromorphone at therapeutic plasma levels. This wearable drug delivery pump ensures reliable, long-term analgesia for dogs, overcoming the limitations of traditional bolus dosing for chronic and moderate pain.
| James S. Gaynor, DVM, MS, DACVAA, DAIPM | The Perfect Pump: Wearable Pumps for Pain Control | Read Paper |
| K. Messenger ; H. Enomoto ; H. Knych ; M. Papich | Pharmacokinetics of Hydromorphone in Dogs after Intravenous Bolus and Delivered Subcutaneously with the RxActuator Mini-Infuser® Infusion Pump | Read Paper |
| Kristen Messenger, Hiroko Enomoto, Melanie Madsen, Heather Knych, and Mark Papich |
Pharmacokinetics of Hydromorphone in Dogs after Intravenous Bolus and Delivered Subcutaneously with the RxActuator Mini-Infuser® Infusion pump |
View Presentation |
Anti Microbial Infusion with Ceftazidime
The RxActuator Mini-Infuser® ensures optimal therapeutic outcomes for time-dependent antimicrobials by delivering a continuous 48-hour subcutaneous infusion of ceftazidime in dogs, eliminating frequent, stressful injections while maintaining steady-state plasma concentrations essential for treating resistant canine bacterial infections.
| Mark G. Papich DVM, MS, DACVCP Melanie Madsen DVM Kristen Messenger DVM, PhD, DACVAA, DACVCP Hiroko Enomoto DVM | Ceftazidime pharmacokinetics in dogs after intravenous injection and delivered with the RxActuator Mini-Infuser infusion pump | Read Paper |